Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
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ODM service for ergonomic pillows Vietnam
Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Ergonomic insole ODM support Vietnam
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Vietnam foot care insole ODM expert
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Smart pillow ODM manufacturer Vietnam
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Taiwan ergonomic pillow OEM supplier
Scientists from the Salk Institute have discovered two distinct neural pathways that mice use to encode mechanical and chemical sensations of itch, with a particular population of neurons transmitting mechanical itch information from the spinal cord to the brain. The identification of separate neural pathways governing itch-scratch responses and chronic itch conditions in mice lays the groundwork for the development of novel therapeutic targets. Itch serves as a defensive alert in animals, acting to prevent the introduction of potentially harmful pathogens into their bodies by parasites. For instance, when a mosquito alights on a person’s arm, they become aware of its touch and instinctively scratch the area to dispel it. This sensation of itchiness arising from a physical stimulus like a crawling insect is termed as “mechanical,” differing from the “chemical” itchiness provoked by irritants such as a mosquito’s saliva following a bite. Despite eliciting the same reaction (scratching), recent investigations by scientists at the Salk Institute have discovered that, in mice, there is a specific brain pathway controlling the mechanical sensation which is separate from the neural pathway that is responsible for encoding the chemical sensation. Identified mechanical itch-responsive neuron (blue) located among cell nuclei (green) in the brainstem. Credit: Salk Institute Key Neurons and Neuropeptide Signals Identified Their findings, recently published in the journal Neuron, show that a small population of neurons relay mechanical itch information from the spinal cord to the brain and identify the neuropeptide signals that regulate both itch types. “This study provides fundamental insights into how these two forms of itch are encoded by the brain and opens up new avenues for therapeutic interventions for patients that suffer from a range of chronic itch conditions, including ectopic dermatitis and psoriasis,” says co-corresponding author Martyn Goulding, professor and holder of the Frederick W. and Joanna J. Mitchell Chair. The discovery builds on previous work in Goulding’s lab that had identified the neurons in the spinal cord that control mechanical itch and not chemical itch. Members of Goulding’s lab teamed up with co-corresponding author Sung Han, assistant professor and holder of the Pioneer Fund Developmental Chair, who had previously found that a small region of the brain serves as an alarm center that fields threat signals, both external and internal from within the body. Han’s team had noticed that a specific group of neurons were crucial for encoding threat signals. Goulding’s lab then decided to focus on these neurons and ask if they play a specific role in relaying mechanical itch signals to this alarm center. From left: Martyn Goulding and Sung Han. Credit: Salk Institute The team used genetic approaches combined with wearable miniaturized microscopes that allowed the researchers to see itch-induced activity in single neurons of mice. The scientists discovered that by removing an inhibitory pathway involved in itch, they could activate a mechanical itch. By observing subsequent activity and changes occurring in the brainstem, they saw that different cells were responding to either mechanical or chemical itch. This allowed the team to classify distinctions between a chemical itch pathway and a mechanical itch pathway and clearly identify the molecules important for regulating them. Chronic Itch and Its Pathological Drivers “We found that if you sensitize one pathway, you can stimulate a pathological itch state, and vice versa,” says Han. “This indicates that these two pathways act together to drive chronic itch.” Next, the scientists plan to examine where in the brain these pathways converge, and then explore the parts of the brain that receive signals that determine the decision of whether to scratch an itch. They also want to better understand how the spinal cord and brainstem differentiate between pain and itch. “The prevalence of chronic itch increases as we age. For this reason, we would also like to understand more about what is happening to the neural circuits that relay itch as we get older,” says Goulding. “Given that chronic itch is an intractable problem, our findings should help leverage the development of new therapies for treating it.” Reference: “Identification of an essential spinoparabrachial pathway for mechanical itch” by Xiangyu Ren, Shijia Liu, Amandine Virlogeux, Sukjae J. Kang, Jeremy Brusch, Yuanyuan Liu, Susan M. Dymecki, Sung Han, Martyn Goulding and David Acton, 5 April 2023, Neuron. DOI: 10.1016/j.neuron.2023.03.013 Other authors include Xiangyu Ren, Shijia Liu, Amandine Virlogeux, Sukjae J. Kang, Jeremy Brusch, and David Acton of Salk, Yuanyuan Liu of the National Institutes of Health, and Susan M. Dymecki of Harvard Medical School. The study was funded by the National Institutes of Health.
A study of herring gull chicks shows a strong preference for seafood over urban-derived foods, like bread and cat food, regardless of their upbringing on urban diets, emphasizing the resilience of their natural dietary inclinations in an urban setting. Research on herring gull chicks in Cornwall indicates that even when raised on urban diets, they prefer fish, suggesting innate dietary preferences persist despite urban environmental influences. This highlights ongoing conservation concerns for gulls as they adapt to decreased fish stocks and increased urban food availability. Seagull chicks raised on an “urban” diet still prefer seafood, new research shows. University of Exeter scientists studied herring gull chicks that had been rescued after falling off roofs in towns across Cornwall, UK. Raised in captivity (before being released), they were given either a “marine” diet consisting mainly of fish and mussels, or an “urban” diet containing mostly bread and cat food. Every few days the gull chicks were presented with a choice of all four foods in different bowls, to test which they preferred – and all gulls strongly favored fish. University of Exeter scientists studied herring gull chicks that had been rescued after falling off roofs. Credit: Emma Inzani “Our results suggest that, even when reared on an ‘urban’ diet of foods found only around people, these chicks might be unlikely to seek out urban foods as adults,” said lead author Emma Inzani, from the Centre for Ecology and Conservation on Exeter’s Penryn Campus in Cornwall. “Human-associated foods are often both reliably present and easy to obtain – but when fish is available they clearly prefer it.” Herring gulls are often seen as a pest in urban areas, where they scavenge for dropped food and in bins, and sometimes take food from people. However, the species is on the UK’s List of Highest Conservation Concern due to ongoing population declines. When presented with all four foods together on days 5, 10, 15, and 35 of the study, both groups consistently favored fish. Credit: Emma Inzani Inzani said a combination of reduced fish stocks in UK waters – coupled with abundant and easy access to food waste in towns – may mean it is not as profitable for gulls to spend a lot of energy going out to sea to forage. Previous research has shown that parent gulls often switch to finding more seafood once their chicks hatch, possibly due to seafood providing more of the nutrients chicks need to grow. In this new study, all 27 chicks had access to food all day, but half of the chicks had urban food for 80% of the day and seafood for 20%, while the other half of the chicks received the opposite diet. When presented with all four foods together on days 5, 10, 15, and 35 of the study, both groups consistently favored fish – and even those that tried the bread rarely ate much of it. Chicks’ preferences for fish found in this study may reinforce the behavior observed in parent gulls to switch to provisioning more marine-sourced foods upon chick hatching. “Animals can live and exploit urban areas for human food waste,” said senior author Dr. Neeltje Boogert. “However, this does not necessarily mean they’re thriving or that they prefer this food, rather than making the best of a bad situation. “More research is needed to investigate how the food young animals receive affects their later life, including their food choices, health, and breeding.” Reference: “Early-life diet does not affect preference for fish in herring gulls (Larus argentatus)” by Emma Inzani, Laura Kelley, Robert Thomas and Neeltje J. Boogert, 11 July 2024, PeerJ. DOI: 10.7717/peerj.17565 The study was funded by the Natural Environment Research Council and the Royal Society.
A groundbreaking project has mapped the DNA of over 9,500 flowering plants, providing new insights into plant evolution and making the data freely available for research in biodiversity and other scientific fields. Credit: SciTechDaily.com The flowering plant tree of life, much like our own family tree, allows us to understand how different species are related to each other. The tree of life is revealed by comparing DNA sequences between different species to identify changes (mutations) that accumulate over time like a molecular fossil record. Our understanding of the tree of life is rapidly improving due to advances in DNA sequencing technology. A vast DNA tree of life brings open access DNA sequences of more than 9,500 flowering plants was recently achieved by scientists from the Royal Botanic Gardens, Kew, together with collaborators from the Kunming Institute of Botany (KIB) of the Chinese Academy of Sciences and around the globe, this invaluable resource lets us answer key questions about modern plant life and look back in time to its origins. Their study was recently published in Nature. Technological Advances in DNA Sequencing A key advantage of the approach is that it can be used to sequence a wide range of plant material, old and new, even when the DNA is badly damaged. The vast treasure troves of dried plant material in the world’s herbarium collections, which include nearly 400 million scientific plant specimens, can now be studied genetically. Angiosperm Tree of Life. Credit: RBG Kew Using such specimens, the researchers sequenced a sandwort specimen (Arenaria globiflora) collected nearly 200 years ago in Nepal and, despite the poor quality of its DNA, were able to place it in the tree of life. They even analyzed extinct plants, such as the Guadalupe Island olive (Hesperelaea palmeri), which has not been seen alive since 1875. In fact, 511 of the species sequenced are already threatened with extinction, according to the International Union for Conservation of Nature Red List, including three more like Hesperelaea that are already extinct. Global Collaboration and Novel Discoveries Of the 9,506 species sequenced for this study, over 3,400 were derived from material sourced from 163 herbaria in 48 countries, with additional material from plant collections around the world (e.g., DNA banks, seeds, and living collections). Among the species sequenced, more than 800 had never had their DNA sequenced before. This sequencing was essential to fill in important knowledge gaps and shed new light on the evolutionary history of flowering plants. The researchers also benefited from publicly available data for more than 1,900 species, highlighting the value of the open science approach to future genomic research. Despite the contrasting biological properties of the nuclear and plastid genomes (e.g., size, copy number, mode of inheritance, recombination, and evolutionary rate), which can lead to conflicting phylogenic trees, the results largely support the mostly plastid-based phylogenetic classification of the Angiosperm Phylogeny Group IV. For example, 58 of the 64 currently accepted orders and 406 of the 416 families were recovered as monophyletic (excluding artifacts). Tanglegram at ordinal level between this work (left) and the APG IV schematic tree (right). Credit: KIB The most striking exception is the non-monophyly of Asteraceae, the largest angiosperm family, which includes sunflowers and their relatives. The tree produced by this study also confirms 85% of the relationships among families recovered by the phylogenomic angiosperm tree using plastomes by scientists from the KIB. Darwin’s “Abominable Mystery” and Evolutionary Insights Flowering plants originated over 140 million years ago, after which they rapidly overtook other vascular plants. Darwin was puzzled by the seemingly sudden appearance of such diversity in the fossil record and wrote: “The rapid development, as far as we can judge, of all the higher plants within recent geological times is an abominable mystery.” Using 200 fossils, the researchers traced their tree of life back in time to show how flowering plants evolved over geological time. They found that early flowering plants did indeed explode in diversity, as Darwin noted. The rapid development of these plants gave rise, shortly after their origin, to over 80% of the major lineages that exist today. However, this trend then declined to a more stable rate for the next 100 million years, until another surge in diversification occurred about 40 million years ago, coinciding with a global drop in temperature. These new findings would have fascinated Darwin and will surely help today’s scientists as they grapple with the challenges of understanding how and why species diversify. The flowering plant tree of life has enormous potential for biodiversity research. This is because, just as one can predict the properties of an element based on its position in the periodic table, the location of a species in the tree of life allows us to predict its properties. The new data will therefore be invaluable in improving many areas of science and beyond. To make this possible, the tree and all its underlying data have been made openly and freely available to both the public and the scientific community, including through the Kew Tree of Life Explorer. The researchers believe that such open access is key to democratizing access to scientific data around the world. Open access will also help scientists make the most of the data, such as combining it with artificial intelligence to predict which plant species may contain molecules with medicinal potential. Similarly, the tree of life can be used to better understand and predict how pests and diseases will affect plants in the future. Ultimately, the researchers note, the applications of this data will be driven by the ingenuity of the scientists who access it. Reference: “Phylogenomics and the rise of the angiosperms” by Alexandre R. Zuntini, Tom Carruthers, Olivier Maurin, Paul C. Bailey, Kevin Leempoel, Grace E. Brewer, Niroshini Epitawalage, Elaine Françoso, Berta Gallego-Paramo, Catherine McGinnie, Raquel Negrão, Shyamali R. Roy, Lalita Simpson, Eduardo Toledo Romero, Vanessa M. A. Barber, Laura Botigué, James J. Clarkson, Robyn S. Cowan, Steven Dodsworth, Matthew G. Johnson, Jan T. Kim, Lisa Pokorny, Norman J. Wickett, Guilherme M. Antar, Lucinda DeBolt, Karime Gutierrez, Kasper P. Hendriks, Alina Hoewener, Ai-Qun Hu, Elizabeth M. Joyce, Izai A. B. S. Kikuchi, Isabel Larridon, Drew A. Larson, Elton John de Lírio, Jing-Xia Liu, Panagiota Malakasi, Natalia A. S. Przelomska, Toral Shah, Juan Viruel, Theodore R. Allnutt, Gabriel K. Ameka, Rose L. Andrew, Marc S. Appelhans, Montserrat Arista, María Jesús Ariza, Juan Arroyo, Watchara Arthan, Julien B. Bachelier, C. Donovan Bailey, Helen F. Barnes, Matthew D. Barrett, Russell L. Barrett, Randall J. Bayer, Michael J. Bayly, Ed Biffin, Nicky Biggs, Joanne L. Birch, Diego Bogarín, Renata Borosova, Alexander M. C. Bowles, Peter C. Boyce, Gemma L. C. Bramley, Marie Briggs, Linda Broadhurst, Gillian K. Brown, Jeremy J. Bruhl, Anne Bruneau, Sven Buerki, Edie Burns, Margaret Byrne, Stuart Cable, Ainsley Calladine, Martin W. Callmander, Ángela Cano, David J. Cantrill, Warren M. Cardinal-McTeague, Mónica M. Carlsen, Abigail J. A. Carruthers, Alejandra de Castro Mateo, Mark W. Chase, Lars W. Chatrou, Martin Cheek, Shilin Chen, Maarten J. M. Christenhusz, Pascal-Antoine Christin, Mark A. Clements, Skye C. Coffey, John G. Conran, Xavier Cornejo, Thomas L. P. Couvreur, Ian D. Cowie, Laszlo Csiba, Iain Darbyshire, Gerrit Davidse, Nina M. J. Davies, Aaron P. Davis, Kor-jent van Dijk, Stephen R. Downie, Marco F. Duretto, Melvin R. Duvall, Sara L. Edwards, Urs Eggli, Roy H. J. Erkens, Marcial Escudero, Manuel de la Estrella, Federico Fabriani, Michael F. Fay, Paola de L. Ferreira, Sarah Z. Ficinski, Rachael M. Fowler, Sue Frisby, Lin Fu, Tim Fulcher, Mercè Galbany-Casals, Elliot M. Gardner, Dmitry A. German, Augusto Giaretta, Marc Gibernau, Lynn J. Gillespie, Cynthia C. González, David J. Goyder, Sean W. Graham, Aurélie Grall, Laura Green, Bee F. Gunn, Diego G. Gutiérrez, Jan Hackel, Thomas Haevermans, Anna Haigh, Jocelyn C. Hall, Tony Hall, Melissa J. Harrison, Sebastian A. Hatt, Oriane Hidalgo, Trevor R. Hodkinson, Gareth D. Holmes, Helen C. F. Hopkins, Christopher J. Jackson, Shelley A. James, Richard W. Jobson, Gudrun Kadereit, Imalka M. Kahandawala, Kent Kainulainen, Masahiro Kato, Elizabeth A. Kellogg, Graham J. King, Beata Klejevskaja, Bente B. Klitgaard, Ronell R. Klopper, Sandra Knapp, Marcus A. Koch, James H. Leebens-Mack, Frederic Lens, Christine J. Leon, Étienne Léveillé-Bourret, Gwilym P. Lewis, De-Zhu Li, Lan Li, Sigrid Liede-Schumann, Tatyana Livshultz, David Lorence, Meng Lu, Patricia Lu-Irving, Jaquelini Luber, Eve J. Lucas, Manuel Luján, Mabel Lum, Terry D. Macfarlane, Carlos Magdalena, Vidal F. Mansano, Lizo E. Masters, Simon J. Mayo, Kristina McColl, Angela J. McDonnell, Andrew E. McDougall, Todd G. B. McLay, Hannah McPherson, Rosa I. Meneses, Vincent S. F. T. Merckx, Fabián A. Michelangeli, John D. Mitchell, Alexandre K. Monro, Michael J. Moore, Taryn L. Mueller, Klaus Mummenhoff, Jérôme Munzinger, Priscilla Muriel, Daniel J. Murphy, Katharina Nargar, Lars Nauheimer, Francis J. Nge, Reto Nyffeler, Andrés Orejuela, Edgardo M. Ortiz, Luis Palazzesi, Ariane Luna Peixoto, Susan K. Pell, Jaume Pellicer, Darin S. Penneys, Oscar A. Perez-Escobar, Claes Persson, Marc Pignal, Yohan Pillon, José R. Pirani, Gregory M. Plunkett, Robyn F. Powell, Ghillean T. Prance, Carmen Puglisi, Ming Qin, Richard K. Rabeler, Paul E. J. Rees, Matthew Renner, Eric H. Roalson, Michele Rodda, Zachary S. Rogers, Saba Rokni, Rolf Rutishauser, Miguel F. de Salas, Hanno Schaefer, Rowan J. Schley, Alexander Schmidt-Lebuhn, Alison Shapcott, Ihsan Al-Shehbaz, Kelly A. Shepherd, Mark P. Simmons, André O. Simões, Ana Rita G. Simões, Michelle Siros, Eric C. Smidt, James F. Smith, Neil Snow, Douglas E. Soltis, Pamela S. Soltis, Robert J. Soreng, Cynthia A. Sothers, Julian R. Starr, Peter F. Stevens, Shannon C. K. Straub, Lena Struwe, Jennifer M. Taylor, Ian R. H. Telford, Andrew H. Thornhill, Ifeanna Tooth, Anna Trias-Blasi, Frank Udovicic, Timothy M. A. Utteridge, Jose C. Del Valle, G. Anthony Verboom, Helen P. Vonow, Maria S. Vorontsova, Jurriaan M. de Vos, Noor Al-Wattar, Michelle Waycott, Cassiano A. D. Welker, Adam J. White, Jan J. Wieringa, Luis T. Williamson, Trevor C. Wilson, Sin Yeng Wong, Lisa A. Woods, Roseina Woods, Stuart Worboys, Martin Xanthos, Ya Yang, Yu-Xiao Zhang, Meng-Yuan Zhou, Sue Zmarzty, Fernando O. Zuloaga, Alexandre Antonelli, Sidonie Bellot, Darren M. Crayn, Olwen M. Grace, Paul J. Kersey, Ilia J. Leitch, Hervé Sauquet, Stephen A. Smith, Wolf L. Eiserhardt, Félix Forest and William J. Baker, 24 April 2024, Nature. DOI: 10.1038/s41586-024-07324-0
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